الرسائل الموجهة للمختصين الصحيين
المنتج | التاريخ | معلومات السلامة | المرفقات |
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Jectin-12® (Cyanocobalamin) |
Cyanocobalamin and the risk of medication error. |
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Xeljanz® (Tofacitinib) |
Increased risk of pulmonary embolism and overall mortality with higher dose of XELJANZ (tofacitinib) for rheumatoid arthritis. |
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Genvoya ® (elvitegravir, cobicistat, emtricitabine and tenofovir alafenamide) |
Increased risk of treatment failure and increased risk of mother-to-child transmission of HIV infection due to lower exposure of elvitegravir and cobicistat during the second and third trimesters of pregnancy. |
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Dapagliflozin |
Risk of Fournier’s gangrene (necrotising fasciitis of the perineum) with Sodium-glucose-Co-Transporter 2 inhibitors (SGLT2i). |
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Adenuric® (Febuxostat) |
Febuxostat (adenuric®): Higher rate of cardiovascular death in gout patients with established cardiovascular disease. |
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Belimumab |
Benlysta (Belimumab) and Risk of serious Depression and/ or Suicidal ideation or Behavior or self-injury. |
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Atezolizumab |
TECENTRIQ® (atezolizumab): A New Important Identified Risk: Immune-related Myositis. |
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Canagliflozin |
Risk of Fournier´s gangrene (necrotising fasciitis of the perineum) with Sodium-Glucose-Co-Transporter 2 inhibitors (SGLT2i). |
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Pembrolizumab |
Keytruda (pembrolizumab): Restriction of indication for the treatment of locally advanced or metastatic urothelial carcinoma in adults who are not eligible for cisplatin-containing chemotherapy. |
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Empagliflozin |
Direct Healthcare Professional Communication on the association of Sodium-Glucose-Co-Transporter 2 inhibitors (SGLT2i) with Risk of Fournier´s gangrene (necrotising fasciitis of the perineum). |