|
Phase I/II Study of a Lentigen® CD19 Chimeric Antigen Receptor (CAR) T Cells in Adult patients with relapsed/refractory CD19 Positive Non-Hodgkin’s Lymphoma (NHL) using a Closed Transduction System
|
Completed
|
CD19-CART
|
1
|
2191301
|
KFSH&RC-R
|
|
Phase I/II Study of a Lentigen® CD19 Chimeric Antigen Receptor (CAR) T Cells in Adult patients with relapsed/refractory CD19 Positive Acute Lymphoblastic Leukemia (ALL) using a Closed Transduction System
|
Completed
|
CD19-CART
|
1/2
|
2191207
|
KFSH&RC-R
|
|
Phase 3, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of PF-07055480 (Recombinant AAV2/6 Human Factor VIII Gene Therapy) in Adult Male Participants with Moderately Severe to Severe Hemophilia A (FVIII:C≤1%)
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Ongoing
|
PF-07055480 (formerly SB-525)
|
3
|
C3731003
|
King Faisal Specialist Hospital and Research Center (Riyadh)
|
|
Phase 3, open label, single arm study to evaluate efficacy and safety of FIX gene transfer with PF-06838435 (rAAV-Spark100-hFIX-Padua) in adult male participants with moderately severe to severe hemophilia B (FIX:C<2%) (BeneGene-2)
|
Ongoing
|
PF-06838435
|
3
|
C0371002
|
KFSH&RC-R
|
|
"Phase 2, Single-Site, Open-Label, Randomized, 2-Arm Parallel Study to Assess the Efficacy and Safety of Ryanodex® (EGL-4104) as Adjuvant Treatment in Subjects With Exertional Heat Stroke (EHS"
|
Completed
|
Dantrolene
|
2
|
EGL-4104-C-1502
|
KFMC
|
|
Phase 2 study of 5 Days azacytidine priming prior to fludarabine, cytarabine and G-CSF combination for patients with relapsed or refractory AML.
|
Ongoing
|
Vidaza
|
2
|
Version 1.1
|
KFMC
|
|
Phase 1 Trial of Ocular Subretinal Injection of a Recombinant Adeno-Associated Virus (rAAV2-VMD2-hMERTK) Gene Vector to Patients with Retinal Disease due to MERTK Mutations
|
Completed
|
rAAV2
|
1
|
rAAV2-VMD2-hMERTK
|
KFSH & RC-R
|
|
Perioperative Ischemic Evaluation-3 Tril (POISE-3)
|
Ongoing
|
tranexamic acid
|
3
|
CT18/008/J
|
King Abdulaziz Medical City NG (Riyadh)
|
|
Perioperative Ischemic Evaluation-3 Tril (POISE-3)
|
Ongoing
|
tranexamic acid
|
3
|
CT18/008/J
|
King Abdulaziz Medical City NG (Riyadh)
|
|
"Open-label, multicenter, single arm, phase II study assessing treatment patient preference for new deferasirox formulation (film-coated tablet) compared to the reference deferasirox dispersible tablet formulation "
|
Ongoing
|
deferasirox
|
2
|
CICL670FIC05
|
KAUH-J
|
